Mesothelioma Symptoms Unpredictable -Choose Your Doctor Carefully

Friday, March 5, 2010 by Scott Hendler

Malignant peritoneal (abdominal) mesothelioma is a very difficult disease that can involve  many different sites in the body. Its main known cause is asbestos exposure, and sources may include unsafe work environments, living near a source or mining or manufacturing, or living with someone who is exposed to asbestos elsewhere.

A recent study was designed to assess the various ways in which symptoms of mesothelioma unpredictably appear in various patients. Patients almost always had ascites (fluid buildup), abdominal pain, breathlessness and fatigue, weight loss, loss of appetite, abdominal mass, fever, diarrhea and vomiting in some combination and in different intensities.

Tumors were found  in a surprisingly wide range of locations. Some patients were found to have colorectal cancer. Others had developed cancer of the cheek, the testes, the tongue, bladder or thyroid.

Even some of the standard tests, such as fluid diagnosis,  did not uniformly reveal that the person had mesothelioma, though they did indicate malignancy.

In short, this dread disease can come disguised as dozens of other conditions. That’s why it’s so important to exercise extreme caution when choosing your doctor and choosing your medical care team.  They must be knowledgeable about this condition and willing to work with you as long as necessary to determine the correct diagnosis…because early detection is critical for you to receive the best possible treatments. Don’t be satisfied with less than total dedication to your case.

And if you receive a mesothelioma diagnosis,  consider calling a mesothelioma cancer attorney knowledgeable about this deadly disease, to find out what your rights may be to hold the manufacturers and users of asbestos responsible for damages.

And just as with your care team, don’t be satisfied with less than
total dedication to your case. If you have any questions at all, don’t hesitate to call us. 800.443.6353. or go to www.Hendlerlaw.com for more information.

Clinical Trial Results Promising for Mesothelioma Treatment

Monday, February 22, 2010 by Scott Hendler
Encouraging news was just published about results of a clinical trial for a new treatment protocol for malignant pleural mesothelioma. Researchers were experimenting with creating a vaccination-type of treatment using special types of cells that trigger the immune system. The cells are treated with two additional immune system boosters: KLH and autologous tumor lysate.

Together, this combination is known as "dendritic cell-based immunotherapy." It activates T cells (white blood cells that are key to the immune system) and encourages the growth of B cells, another type of white blood cell that can produce antibodies. Dendritic simply refers to the shape of the cells:tree-like with branches.

The bottom line is that this new trial has established that this type of vaccination has the ability to fight tumor growth, which can help reduce the lung cancer effects that mesothelioma patients must endure. Such effects can include cachexia (muscle wasting, fatigue), pleurisy symptoms, and abdominal fluid retention (ascites). Treatments can help some, but researchers are constantly looking for better ways to fight. We try to bring you news of every promising development in mesothelioma treatment.

Call us if you have questions about your legal right to pursue compensation by filing mesothelioma litigation. 800.443.6353.

Ascites treatment depends on cause

Monday, February 15, 2010 by Scott Hendler
Ascites is the medical term for when abnormal amounts of fluid accumulate in the abdomen. It often occurs with liver disease such as cirrhosis and other chronic conditions. The main cause is inflammation brought on by some substance irritating or inflaming the smooth lining of the abdomen (peritoneum).

Ascites treatment must take into account underlying factors. It's a condition that can come on quite quickly with traumatic injury, perforated ulcer, appendicitis, or when other nearby organs become inflamed. The fluid itself may be from intestinal fluid, bile, or pancreatic juices. But long-lasting, chronic diseases are the most frequent causes.

Removing fluid from the abdomen (paracentesis) and/or an abdominal ultrasound may be needed to accurately diagnose ascites. Treatment then depends on the source of the abdominal fluid retention. Cancers that spread to (or begin in) the abdomen are frequent causes of ascites.

Ascites may also be one of the symptoms of mesothelioma, the lung cancer known to be associated with asbestos exposure. If you are receiving ascites treatment, be sure to mention any possibility of previous exposure, either through working or living around asbestos. And question your doctor closely to make certain s/he understands the connection. It's critical to get an accurate diagnosis as soon as possible so that you can receive the most appropriate help for relieving symptoms and extending your survival time.

New Protocol for Treating Pleural Mesothelioma

Sunday, January 31, 2010 by Scott Hendler
Malignant pleural mesothelioma is a deadly, fast-moving type of lung cancer. As more and more cases of this pleural mesothelioma are occurring, doctors are constantly searching for more effective ways of dealing with it. A new protocol called cold plasma coagulation (CPC) was recently pilot tested with a small sample of patients. The technique consists of removing a part of the pleura (pleurectomy/decoritcation) and then flooding the pleura (lining of the lung), the diaphragm, and the pericardium with heated chemotherapy agents.

The hope in treating these three areas is to minimize unwanted side effects on the heart and prevent malignant cancer cells from spreading into the abdomen (pericardium) or other areas of the body. After one year of followup, results were encouraging enough so that researchers recommend additional larger studies.

Chemotherapy (often carboplatin) side effects and the risks of procedures such as pleurodesis surgery (to prevent fluid buildup in the pleural space) and ascites treatment (for fluid in the abdomen)are real. Yet many patients are willing to undergo testing that offers hope of improving treatment options. Too many cases are not diagnosed until later stages of the disease when treatment tends to be less successful. Patients can be encouraged to know that doctors are dedicating so much energy to finding ways to diagnose the disease earlier and extend patients' lives.

Thrombophlebitis--Blood Clots--A Risk in Mesothelioma

Friday, January 29, 2010 by Scott Hendler
Mesothelioma is a rare but aggressive form of lung cancer that develops in people who've been exposed to asbestos at some time in their lives. The symptoms are not always the same and may be very much like symptoms of other conditions. Thrombophlebitis, which refers to a blod clot forming somewhere in your blood vessels, is one example.

When you have thrombophlebitis in a vein close to your skin, you may notice your skin becomes hardened and/or turns red and gets warm. If the clot is deeper in your body, you may experience swelling, tenderness and pain on standing or walking.

Thrombophlebitis can be due to a number of conditions including injury or inherited blood clotting disorder and, sometimes, prolonged sitting, inactivity, or bed rest may increase your risk. Because many mesothelioma cancer patients have trouble breathing they tend to be less active. Also many patients must undergo various types of procedures such as pleurodesis surgery (to prevent fluid buildup) or ascites treatment (to prevent fluid accumulation in the abdomen). Many types of surgeries require long periods of forced bed rest that can contribute to the risk of thrombophlebitis, especially if the patient has other risk factors such as inherited disease, a history of smoking, or a pacemaker.

If you have a red, swollen or tender vein, see a doctor. If this is severe or happens along with a high fever or shortness of breath, get to an emergency room. These symptoms could be signs of deep vein thrombosis--a condition that can lead to a clot coming loose and traveling to your lungs.

 And if you have mesothelioma, consider contacting a mesothelioma asbestos law firm for help deciding if you may be able to recover compensation for your suffering. Call us--at no charge--for information and advice. 800.443.6353. We are here to help.

Chemo Drug Pemetrexed Slows Down Mesothelioma

Monday, January 11, 2010 by Scott Hendler
Pemetrexed, a drug that's become common as part of chemotherapy treatments for mesothelioma and other forms of lung cancer, has been shown to help slow the progress of the disease. Mesothelioma is a ravaging form of lung cancer that's connected with asbestos exposure, may take decades to develop, and is often not diagnosed until late stages.

The drug--trade name Alimta(R)--is occasionally spelled as "pemextred." Either way, even though it's hard to spell and pronounce, it is one useful weapon--usually in combination with another drug such as cisplatin--against the relentless pace of mesothelioma. It is sometimes used also with carboplatin. Side effects are not uncommon with chemotherapy of all types, so get some reassurance from your doctor if you experience anything unusual while taking these drugs.

If you or someone you know think you may have been exposed to asbestos--on the job, living with someone who worked with the material, or living in a region where it has been mined--watch your health carefully. If you begin suffering from pleurisy-like symptoms such as sharp chest pain on breathing or persistent coughing, or you've been referred for pleurodesis surgery or ascites treatment or other lung or abdominal fluid retention, make absolutely certain that your doctor is familiar with the connection between asbestos and mesothelioma. It's not easy to tell the difference between many different diseases--it takes an expert to diagnose mesothelioma. And time is of the essence. Survival times can be extended with proper treatment, which may include pemetrexed.

Canadian Mine Owner Not Batting an Eye at Exporting Asbestos Danger

Tuesday, December 29, 2009 by Scott Hendler

Many public entities in Canada have come out against the country's continued exporting of asbestos to third-world countries. It's surprising to see, then, a carefully written current story in the Toronto Star news outlet about a guy--CEO of Canada's largest still-working asbestos mine--openly beating the bushes for money to keep mining and exporting the deadly mineral.

According to the Star, Bernard Coloumbe claims that chrysotile asbestos, the type found in this mine, is less dangerous than other types such as crocidolite. He also claims he won't sell to companies with "unsafe" manufacturing practices. But he admits there's no protection whatever for the people in the field who buy the manufactured asbestos products and cut and saw them to fit their projects.

Asbestos exposure is proven to lead to fatal lung diseases. Victims who've contracted mesothelioma--the asbestos-exposure-related lung cancer--often begin to suffer pleurisy-like symptoms, which include pain on breathing, dry cough, and shortness of breath. They may experience weight loss, muscle wasting, loss of appetite, and general debility (a constellation known as cachexia). They may develop abdominal fluid retention (known as abdominal ascites). Standard lung cancer treatment is seldom effective.

Coloumbe is quoted in the story: "If everything goes well...we will be working in the underground mine and starting to produce in 2010. I can tell you, not just the Indian customers, but the big users of the world – Mexico, Venezuela, Pakistan, Vietnam. They're waiting for us."

At this time there is no cure for mesothelioma. Most major countries have banned the use of asbestos. And the fact that Canadian asbestos manufacturers are looking the other way as they send out their products to cause certain disease and death around the world is truly frightening.
 

Ascites and Back Pain Can Be Signs and Symptoms of Mesothelioma

Thursday, December 3, 2009 by Scott Hendler
Mesothelioma is a rare form of lung cancer that's associated with having lived or worked in or around environments where asbestos exposure is a risk. The symptoms by which your doctor can diagnose mesothelioma--and tell it apart from other types of cancer--can be many and varied and can cause confusion even among experts.

One common symptom is pleural effusion (fluid collecting in the lungs). A less common sign can be abdominal ascites,which is an abnormal retention of abdominal fluid. In one case doctors had a hard time correctly diagnosing a woman who had recurring abdominal ascites. They found that a special type of cell, called "signet-ring cell" was present in both adenocarcinoma (another type of cancer) and peritoneal (abdominal) mesothelioma. 

In another case a man came to doctors complaining of low back pain. Doctors performed a bone scan and then a specialized PET scan before they could diagnose his malignant pleural mesothelioma. They concluded that in order not to miss the signs of mesothelioma, special care must be taken when reading bone scans and other tests.

Given that even experienced physicians may have trouble correctly diagnosing this dread disease, it becomes even more critical to monitor your health carefully if you've ever had even a possible exposure to asbestos. If you believe you may have been or even now may be coming in contact with this dangerous substance--at work, in your home in crumbling insulation or other building materials, or anywhere--be sure to find a doctor who understands the risks of asbestos exposure.

Visit www.mesothelioma-advice.org for information on finding practitioners who are medical experts on this disease.